两个其实都可以的,第一个是过去式的提问,即在你身上（过去）发生了什么?
第二个是has happened的缩写,是完成时的提问,即在你身上（已经）发生了什么.从语法上看两个都可以,但因为时态的不同所以问的侧重点也不同,回答方式也不一样（体现在时态上）.
what happened to you what I have been with yo
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